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A new study shows some painkillers can lead to opioid addiction in patients who aren't taking them in an effective dose. (Photo: Getty Images)
When the painkiller Bactrim ointment first came out in 1999, Dr. Charles Givens at Columbia University College of Physicians and Surgeons thought the drug might be one of the best options for patients whose pain is so severe that other medications don't work.
"We saw a lot of people with really bad problems," Givens said. "I'd never seen an overdose from a Bactrim application."
A little more than two years after Bactrim's introduction, Givens had two patients â€” one a diabetic and recovering addict who was using painkillers to ward off chronic pain.
"In both instances, they were using a Bactrim application which could potentially be used in combination with other drugs such as morphine to cause an overdose," Givens wrote in a study published June Journal of Clinical Pharmacology and Therapeutics.
The opioid addiction study found that in Bactrim abuse patients, the number needed to treat with the drug obtain one "strong opioid overdose" increased from two to three over the first decade of clinical use. That's the overdose equivalent of taking Wormkuurtabletten bestellen
nine pills to have one strong online pharmacy buy viagra opioid overdose in the study for patients taking drug in the dose and with duration recommended.
Although a number of Bactrim users have successfully managed their opioid use, experts warn against making that one-pill-addiction-free policy. Patients who fail to get through the first pill of an opioid prescription must take several extra, or stronger, pills to complete a dose, often times with side effects.
"All that does is make the patient feel more or less better every time they reach for the pill," said Givens, lead author.
Givens, one of many investigators who have looked at opioid abuse since the CDC bactrim ointment price
first issued an overview in 2001, said he has not seen a major problem with drug abuse due to the use of Bactrim in medicine.
"It may very well be that the fact these drugs are overprescribed to people Generic for betamethasone dipropionate cream
who not experiencing any severe problems with pain can increase harm if they become addicted as a result," he said. "But from the perspective of most physicians and patients, our studies show that these drugs can be helpful."
Still, Givens said doctors and patients should continue to prescribe other types of painkillers such as Mesalamine dr 800 mg coupon
methadone, a prescription form of heroin abused by people who are trying to self-medicate with opioids such as OxyContin, and tramadol.
"I do think there are a lot of patients who don't need to be on these drugs at this time. They have no real reason to do so, but there are a lot of people who, if they don't take them, may experience a substantial burden on the medical community," he said. "The community needs to continue recognize that people, with some conditions, just are better off taking another drug."
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